
Understanding Health Testing and
Risk Factors For Poodles
Informed Choices, Healthier Puppies
—Support Responsible Breeders
At High Desert Companions, we believe that responsible breeding begins with knowledge—and that means complete, transparent health testing. Following the gold standards set by the Poodle Club of America, and the Orthopedic Foundation for Animals (OFA), we screen our dogs for all relevant genetic and structural conditions to ensure we’re making the best possible choices for our puppies and their future families.
Understanding inherited diseases, how they work, and what risk factors exist is crucial for ethical breeding. It allows us to make informed pairings that reduce the likelihood of health issues, preserve the integrity of the breed, and support the long-term well-being of every dog we bring into the world.
We’re genuinely pleased that you’re taking the time to research health testing for your future pet and family member—it shows a deep level of care and responsibility. Supporting that kind of initiative is truly my passion. That’s why we’re committed to providing clear, honest information so you feel confident, informed, and fully equipped to make the best decisions for your future companion.
While breeders who fully test their breeding dogs may charge more, the value they offer in peace of mind, quality, and long-term savings on veterinary care is immeasurable. Choosing a breeder who prioritizes health testing not only protects your puppy—it supports the kind of breeding that truly makes a difference.

Do you have a Poodle/Doodle mix?
It’s important to remember that all Doodles and Poodle mixes inherit genetic health risks from every breed in their lineage—not just the Poodle! To fully understand and manage your dog’s health, you need to research the health conditions and structural traits of all breeds involved in the cross.
Foundations of a Healthy Poodle:
What to Test and Why
Ethical, responsible breeding begins with science-backed health screening. We follow the recommendations of the Orthopedic Foundation for Animals (OFA), and the Poodle Club of America.
DNA testing allows us to identify carriers of inherited diseases before they are passed to the next generation. Combined with orthopedic screening, this proactive approach protects both our breeding program and the families who trust us with their companions.
Key DNA Tests Recommended for Poodles:
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CDDY/IVDD – Chondrodystrophy & Intervertebral Disc Disease: associated with spinal disc degeneration.
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PRA-PRCD – Progressive Retinal Atrophy: leads to gradual vision loss and eventual blindness.
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vWD Type I – von Willebrand Disease: an inherited clotting disorder.
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DM – Degenerative Myelopathy: a progressive neurological condition affecting mobility.
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MAC – Macrothrombocytopenia: affects blood platelets, usually asymptomatic.
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Osteochondrodysplasia (Skeletal Dysplasia 2): a skeletal disorder more common in Toy and Miniature Poodles.
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NEWS – Neonatal Encephalopathy with Seizures: a fatal condition in young puppies.
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GM2 Gangliosidosis: a rare, fatal neurodegenerative condition.
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ACVO Eye Examination. Results registered with OFA.
What the DNA Results Mean:
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Clear: The dog does not carry the mutation and cannot pass it on.
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Carrier: The dog carries one copy of the mutation; not typically affected, but can produce affected offspring if paired with another carrier.
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Affected: The dog has two copies of the mutation and is more likely to express the condition.
Orthopedic Screening:
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OFA Patella & Legg-Calvé-Perthes Disease Screening: Important for Toy and Miniature Poodles prone to kneecap or femoral head disorders.
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OFA Hip & Elbow Evaluations: Radiographs assessed by board-certified radiologists to detect signs of dysplasia.
AND OR
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PennHIP Evaluation: Measures hip joint laxity to assess early risk of developing hip dysplasia—more precise than standard OFA scoring.
OFA (Orthopedic Foundation for Animals)
– Hip & Elbow Ratings
Hips:
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Excellent: Superior joint conformation, very tight and well-formed hips.
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Good: Normal, healthy hip joints with no signs of dysplasia.
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Fair: Slightly less than ideal, but still considered within normal limits.
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Borderline: Not clearly normal or dysplastic—recheck in 6 months.
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Mild/Moderate/Severe Dysplasia: Signs of joint looseness or degeneration; not recommended for breeding.
Elbows:
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Normal: No evidence of elbow dysplasia.
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Grade 1, 2, 3 Dysplasia: Increasing severity of joint abnormalities or arthritic changes.
PennHIP (University of Pennsylvania Hip Improvement Program)
PennHIP evaluates hip laxity (looseness) using a Distraction Index (DI) from 0 to 1+:
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Lower DI (closer to 0): Tighter hips, lower risk of developing hip dysplasia.
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Higher DI (closer to 1): Looser hips, higher risk for dysplasia.
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Breed Average Benchmark: Each DI is compared to the breed average—dogs with a DI lower than the breed median are considered better candidates for breeding.
Example: For Poodles, a DI under 0.30–0.40 is considered ideal.
It’s easy to be impressed by claims like “clear on 257 diseases,” but most purebred dogs are only at risk for a small handful of those. That’s because genetic mutations are limited to each breed’s gene pool.
Truly responsible breeding goes beyond DNA. It means combining genetic screening with physical, structural, and temperament evaluations to rule out issues that can lead to disease expression down the line.
In the following sections, we’ll take a closer look at each of these conditions—what they are, how they’re inherited, their risk levels, and how you can reduce the chances of your dog being affected through informed care and responsible choices.
Understanding CDDY (Chondrodystrophy & Intervertebral Disc Disease)
CDDY, or Chondrodystrophy, is a genetic condition linked to abnormal cartilage development and a predisposition to Intervertebral Disc Disease (IVDD)—a spinal condition that can cause pain, nerve damage, or even paralysis. This condition is caused by a mutation in the FGF4 retrogene on chromosome 12, which weakens the intervertebral discs, making them more susceptible to degeneration and herniation.
Why Genetic Testing Matters
Genetic testing for CDDY is widely available and essential for responsible breeders. The test determines whether a dog has:
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0 Copies (Clear): No increased genetic risk.
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1 Copy (Carrier): Mildly increased risk; not typically symptomatic but may pass the mutation to offspring.
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2 Copies (At-Risk): Significantly increased genetic risk of IVDD, especially if paired with certain environmental stressors.
Fixed vs. High-Risk Breeds
Some breeds are “fixed” for the CDDY gene, meaning nearly all individuals in the breed carry two copies of the mutation. These include:
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Dachshunds
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French Bulldogs
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Beagles
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Cocker Spaniels
In these breeds, IVDD affects approximately 20–65% of individuals, often early in life due to their long backs and short, heavy bodies—structural traits that place more stress on the spine.
Poodles are also considered fixed for CDDY, typically testing with two copies of the gene. However, the actual clinical risk of IVDD in Poodles is dramatically lower—with studies estimating incidence at just 1–2% across all sizes, and 3-15% in poodles that have 2 copies
Why the Difference? It’s in the Structure.
The reason for this lower risk in Poodles comes down to conformation. Poodles are bred to maintain a square, balanced build, with height from withers to ground nearly equal to their length from chest to rear. This proportion reduces pressure on the spine and evenly distributes weight across the body, minimizing mechanical strain on the intervertebral discs.
By contrast, high-risk breeds often have a long body with short legs (a “long and low” structure), which places extra mechanical stress on the spine—making them more vulnerable to disc disease even with the same genetic risk.
Environmental Risk Still Matters
Even though the risk in Poodles is low, environmental factors can still trigger disc issues in genetically at-risk dogs:
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Excessive jumping (especially off furniture)
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Obesity
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Rough play or repeated spinal strain
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High-impact activity in puppies or during growth periods
Responsible care—including safe handling, controlled exercise, and maintaining a healthy weight—can dramatically reduce the chance of problems in dogs with CDDY.
CDDY, or Chondrodystrophy, is a genetic condition linked to abnormal cartilage development and a predisposition to Intervertebral Disc Disease (IVDD)—a spinal condition that can cause pain, nerve damage, or even paralysis. This condition is caused by a mutation in the FGF4 retrogene on chromosome 12, which weakens the intervertebral discs, making them more susceptible to degeneration and herniation.


PRA-PRCD – Progressive Retinal Atrophy (Progressive Rod-Cone Degeneration)
Description:
PRA-PRCD is a hereditary, degenerative eye disorder that affects the retina—the light-sensitive tissue at the back of the eye. In affected dogs, photoreceptor cells (rods and cones) gradually deteriorate, leading to night blindness first, followed by complete vision loss. Onset varies but typically begins between 3 and 7 years of age.
It is recessively inherited, meaning both parents must carry the gene to produce affected offspring.
Genotypes & Risk Levels in Poodles:
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Clear (N/N): ~65–75% of Poodles
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The dog does not carry the PRA-PRCD mutation.
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Zero risk of developing or passing the disease.
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Carrier (N/PRA): ~20–30%
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Carries one copy of the mutated gene.
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The dog will not develop PRA, but can pass it to offspring.
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Safe to breed only to Clear (N/N) partners to avoid affected puppies.
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Affected (PRA/PRA): ~1–3%
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Has two copies of the gene and is at high risk of developing the disease.
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Vision typically begins to decline in early adulthood, progressing to full blindness.
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Not painful and dogs adapt well, but genetic counseling is advised.
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Lifestyle Management & Support Strategies:
For Affected (PRA/PRA) dogs or those starting to show vision loss:
Environmental Management
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Avoid moving furniture; keep layout consistent to help the dog memorize its surroundings.
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Use textured rugs or mats as “pathways” to key locations like water bowls or beds.
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Install baby gates near stairs or dangerous areas.
Safety & Enrichment
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Keep the dog on-leash in unfamiliar places to prevent falls or injury.
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Use scent-based toys and food puzzles to stimulate other senses.
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Teach voice or touch commands to help guide the dog.
Veterinary Monitoring
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Have your vet perform regular ophthalmic exams to monitor progression.
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Supplements like omega-3 fatty acids, lutein, and antioxidants may support eye health, though they do not stop progression.
Breeding Considerations
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Do not breed affected dogs.
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Carriers can be responsibly bred to Clear dogs to maintain genetic diversity without producing affected pups.
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Always test breeding pairs to avoid at-risk combinations.
ACVO Eye Examination in Poodles
Protecting Vision, Preserving Bloodlines
The American College of Veterinary Ophthalmologists (ACVO) Eye Examination is an essential screening tool for identifying inherited eye diseases in dogs, especially in breeds like Poodles that are predisposed to certain ocular conditions. The results of these exams can be officially registered with the Orthopedic Foundation for Animals (OFA), contributing to transparent, responsible breeding practices.
What Is the ACVO Eye Exam?
The ACVO Eye Examination is a non-invasive, in-clinic evaluation conducted by a board-certified veterinary ophthalmologist. The purpose is to detect heritable eye disorders that could affect a dog’s health or quality of life—or be passed on to future generations.
This exam screens for conditions such as:
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Progressive Retinal Atrophy (PRA)
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Cataracts
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Distichiasis (extra eyelashes)
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Entropion (inward rolling eyelids)
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Retinal dysplasia
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Optic nerve hypoplasia
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Glaucoma predisposition
It involves pupil dilation and a careful inspection of all eye structures using specialized equipment.
Why It Matters for Poodles
Poodles—particularly the Miniature and Toy varieties—can be genetically predisposed to several eye conditions. Even when no symptoms are present, affected dogs can silently carry genes that may pass issues to their offspring.
Routine ACVO exams help breeders:
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Confirm their dogs are free from visible ocular disease.
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Make informed breeding decisions.
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Preserve the breed’s long-term vision and quality of life.
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Demonstrate a commitment to health transparency.
Registering with OFA
Once the exam is complete, results can be submitted to the Orthopedic Foundation for Animals (OFA) to be permanently recorded in the public health database.
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Owners receive a certificate with the exam findings.
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The OFA assigns a CERF number (Canine Eye Registration Foundation), even though CERF has merged into OFA's database.
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Dogs must be re-examined annually to maintain current certification, as many eye conditions are progressive.
The OFA public database allows breeders and buyers to verify a dog’s eye health as part of their pedigree research—a valuable tool for selecting breeding pairs.
ACVO + Genetic Testing = Full Picture
While the ACVO eye exam identifies visible or developing eye issues, it does not test for genetic markers. To fully protect your breeding program:
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Pair annual ACVO exams with genetic testing for conditions like PRA-PRCD.
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Use both tools to identify carriers, at-risk, and clear dogs.
Together, they create a comprehensive vision-health profile and help reduce the risk of passing on heritable blindness or other eye diseases.
DNA Testing Continued:
vWD Type I – von Willebrand Disease
Description:
An inherited bleeding disorder caused by a deficiency in von Willebrand factor, a protein essential for normal blood clotting.
Genotypes & Risk Levels:
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Clear (N/N): No copies of the mutation. Not at risk or a carrier.
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Carrier (N/vWD1): One copy. Not typically symptomatic but can pass the gene to offspring.
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At Risk/Affected (vWD1/vWD1): Two copies. May experience prolonged bleeding after injury or surgery.
Lifestyle Management:
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Avoid trauma, especially to gums, claws, or areas prone to injury.
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Notify your vet before surgeries or dental cleanings—extra clotting precautions may be needed.
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Limit rough play or activities with high risk of cuts/bruises.
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Regular check-ups to monitor clotting ability if the dog is affected.
DM – Degenerative Myelopathy
Description:
A progressive disease of the spinal cord that leads to hind limb weakness, paralysis, and eventually, loss of mobility. Onset is usually after 7 years of age.
Genotypes & Risk Levels:
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Clear (N/N): No risk of developing or passing it on.
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Carrier (N/DM): One copy. Unaffected but can pass the mutation.
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At Risk (DM/DM): Two copies. At higher risk for developing symptoms in later life, but not all affected dogs will show signs.
Lifestyle Management:
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Keep your dog active with low-impact exercise (e.g., swimming, walking).
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Avoid obesity to reduce strain on joints and spine.
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Regular veterinary neurologic assessments in aging dogs.
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Supplements that support joint and nerve health (e.g., omega-3s, glucosamine) may be recommended.
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Early signs (e.g., dragging rear paws) should be assessed promptly.
MAC – Macrothrombocytopenia
Description:
A blood platelet disorder characterized by fewer but larger platelets. Usually asymptomatic, but may lead to mild bleeding tendencies.
Genotypes & Risk Levels:
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Clear (N/N): Normal platelet counts and function.
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Carrier (N/MAC): Usually normal. No health concerns.
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Affected (MAC/MAC): May have mild bleeding during surgery or injury but typically lead normal lives.
Lifestyle Management:
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Inform your vet before any surgery to monitor clotting times.
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Avoid unnecessary medications that could thin blood (e.g., NSAIDs without vet advice).
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Keep routine vet records updated with platelet status.
Osteochondrodysplasia (Skeletal Dysplasia 2)
Description:
A condition affecting bone growth, leading to disproportionate dwarfism—shortened limbs and skeletal deformities. Seen more in Toy and Miniature Poodles.
Genotypes & Risk Levels:
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Clear (N/N): No risk.
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Carrier (N/SD2): Unaffected, but may pass on.
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Affected (SD2/SD2): Two copies result in abnormal growth and a dwarfed appearance.
Lifestyle Management:
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Avoid jumping from heights (furniture, stairs) to prevent joint injuries.
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Use ramps or steps to protect joints.
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Monitor for early signs of arthritis or orthopedic issues.
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Provide joint-supportive supplements early.
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Maintain a lean body weight to minimize stress on limbs.
NEWS – Neonatal Encephalopathy with Seizures
Description:
A fatal autosomal recessive brain disorder. Puppies are born seemingly normal but develop severe neurological symptoms (e.g., seizures, lack of coordination) within days and die or are euthanized shortly after.
Genotypes & Risk Levels:
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Clear (N/N): No risk.
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Carrier (N/NEWS): One copy. Unaffected but may pass it on.
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Affected (NEWS/NEWS): Two copies. Puppies die shortly after birth.
Lifestyle Management:
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This condition is fatal and not manageable once symptoms appear.
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Prevention through genetic testing is essential. Never breed two carriers.
GM2 Gangliosidosis
Description:
A rare and fatal lysosomal storage disorder. It affects the central nervous system, leading to neurological decline, motor dysfunction, and early death.
Genotypes & Risk Levels:
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Clear (N/N): Safe.
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Carrier (N/GM2): One copy. No symptoms, can pass it on.
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Affected (GM2/GM2): Two copies. Fatal—symptoms often begin before 6 months of age and worsen quickly.
Lifestyle Management:
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Like NEWS, this disease is not treatable—affected puppies generally do not live beyond a year.
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Prevention by screening both parents is the only safeguard.


Orthopedic Screening for Poodles:
Why It Matters
Orthopedic health is a critical aspect of responsible breeding and long-term care in Toy and Miniature Poodles. While these graceful companions are known for their agility and intelligence, they can also be genetically predisposed to joint and skeletal issues—especially in the knees and hips. Early detection through orthopedic screening can help prevent discomfort, promote mobility, and support ethical breeding decisions.
Here’s a breakdown of the most essential orthopedic evaluations for Poodles:
OFA Patella Evaluation & Legg-Calvé-Perthes Disease Screening
Why it matters:
Toy and Miniature Poodles are particularly prone to luxating patellas (slipping kneecaps) and Legg-Calvé-Perthes Disease, a condition involving deterioration of the femoral head (the ball part of the hip joint).
OFA Patella Evaluation checks for:
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Stability of the kneecap (grades 0–4)
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Risk of dislocation
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Proper alignment of the femur and tibia
Legg-Calvé-Perthes Disease Screening includes:
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Clinical orthopedic exam
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X-rays to detect changes in bone density or joint structure
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Often recommended between 6 and 12 months of age
Who should be tested:
All breeding dogs under 20 lbs should receive patella exams, and those used for breeding in Toy or Miniature lines should also be screened for Legg-Calvé-Perthes to ensure they are not unknowingly passing on risk factors.
OFA Hip & Elbow Evaluations
What it is:
This traditional orthopedic screening method involves taking radiographs (X-rays) that are evaluated by three board-certified veterinary radiologists at the Orthopedic Foundation for Animals (OFA). Results are graded based on joint conformation and signs of hip or elbow dysplasia.
When it’s done:
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Dogs must be at least 24 months old for official OFA certification.
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Preliminary evaluations can be done as early as 4 months and are often used to assess breeding prospects before full maturity.
Why it matters:
Hip and elbow dysplasia can severely impact a dog’s quality of life, causing pain, lameness, or arthritis. Early identification helps breeders make informed decisions and allows owners to adapt care strategies if needed.
PennHIP Evaluation
What it is:
PennHIP (developed by the University of Pennsylvania) is a cutting-edge radiographic technique that measures hip joint laxity—how loosely the femoral head fits into the hip socket.
Why it’s more precise than OFA alone:
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PennHIP can detect predisposition to hip dysplasia as early as 16 weeks of age.
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It provides a Distraction Index (DI)—a numerical score that correlates with long-term risk for degenerative joint disease.
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It can detect subtle joint looseness even before bone changes appear on X-rays.
Ideal candidates:
Breeding dogs of any size can benefit, but it's especially valuable in lines where hip dysplasia has been observed or suspected. It’s also helpful for performance dogs or those engaged in agility and active lifestyles.
OFA (Orthopedic Foundation for Animals)
– Hip & Elbow Ratings
Hips:
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Excellent: Superior joint conformation, very tight and well-formed hips.
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Good: Normal, healthy hip joints with no signs of dysplasia.
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Fair: Slightly less than ideal, but still considered within normal limits.
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Borderline: Not clearly normal or dysplastic—recheck in 6 months.
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Mild/Moderate/Severe Dysplasia: Signs of joint looseness or degeneration; not recommended for breeding.
Elbows:
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Normal: No evidence of elbow dysplasia.
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Grade 1, 2, 3 Dysplasia: Increasing severity of joint abnormalities or arthritic changes.
PennHIP (University of Pennsylvania Hip Improvement Program)
PennHIP evaluates hip laxity (looseness) using a Distraction Index (DI) from 0 to 1+:
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Lower DI (closer to 0): Tighter hips, lower risk of developing hip dysplasia.
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Higher DI (closer to 1): Looser hips, higher risk for dysplasia.
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Breed Average Benchmark: Each DI is compared to the breed average—dogs with a DI lower than the breed median are considered better candidates for breeding.
Example: For Poodles, a DI under 0.30–0.40 is considered ideal.
Summary: A Sound Foundation Starts with Screening
Responsible breeders and devoted owners alike should prioritize orthopedic health screening. These evaluations not only protect the integrity of the breed, but also ensure puppies are set up for long, active, and pain-free lives.
📌 OFA Patella
• Age: 12+ months
• Checks: Luxating Patellas
• For: Toy & Miniature Poodles
📌 Legg-Calvé-Perthes
• Age: 6–12 months
• Checks: Femoral Head Disease
• For: Toy Poodles <15 lbs
📌 OFA Hips & Elbows
• Age: 24+ months (Prelims from 4+)
• Checks: Hip & Elbow Dysplasia
• For: All Breeding Dogs
📌 PennHIP
• Age: 16+ weeks
• Checks: Hip Laxity
• For: Breeding/Performance Dogs
How to Look Up OFA Scores & Evaluate Orthopedic Health in Breeding Dogs
Orthopedic screening—particularly for hip and elbow dysplasia, patellas, and Legg-Calvé-Perthes Disease—is an essential part of selecting quality breeding dogs. But evaluating a dog’s health isn’t just about checking their individual scores. You should also assess the consistency of sound orthopedic health in their lineage, including siblings, parents, grandparents, and even aunts/uncles.
Here’s how to do it step by step:
Step 1: Visit the OFA Website
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Go to www.ofa.org
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Click on the “Search OFA Records” tab at the top.
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You can search by:
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Dog’s registered name
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Dog’s registration number
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Partial name or kennel prefix (if you’re browsing lines)
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Tip: Use the dog’s full AKC-registered name for the most accurate results.
Step 2: Review the Dog’s OFA Record Page
Once you’ve selected a dog, you’ll see a page with a list of all recorded health tests. Focus on the orthopedic categories:
Key Evaluations:
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Hips – Rated as:
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Excellent
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Good
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Fair
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Borderline
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Mild/Moderate/Severe Dysplasia (these indicate a failed certification)
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Elbows – Normal or Grade 1–3 (1–3 indicating dysplasia)
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Patellas – Normal or Grades 1–4 (grades indicate increasing severity of luxation)
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Legg-Calvé-Perthes – Normal or Affected
Each record will show:
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Age at time of evaluation
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Final result
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Registry (OFA, PennHIP, etc.)
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If radiographs were preliminary or official
Step 3: Examine the Dog’s Relatives
At the bottom of the OFA record, you’ll find a "Vertical Pedigree"—this is an essential tool for evaluating risk from a genetic standpoint.
What to look for:
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Consistency of good scores (e.g., Good or Excellent hips) in:
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Both parents
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Siblings (especially full littermates)
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Grandparents
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Aunts, uncles, half-siblings
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Avoid lines where:
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Most littermates or parents have “Fair” or below scores.
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There’s a pattern of failed hip or elbow certifications in close relatives.
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One “Excellent” is surrounded by a sea of “Poor” relatives—that’s often a statistical outlier.
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Why This Matters:
Genetics is about probability. Even if the individual dog has an “Excellent” rating, if its parents or siblings have mild or severe dysplasia, that dog still carries genetic material likely to pass on orthopedic problems.
Example:
If two parents produce one pup with Excellent hips and three with Moderate dysplasia, it means the genetic background is unstable. That excellent pup may look like a good candidate but is statistically more likely to pass on bad hips compared to a dog whose litter and family consistently have Good/Excellent scores.
Step 4: Cross-reference with PennHIP (if available)
If the breeder also shares PennHIP results, review the Distraction Index (DI):
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A lower DI (0.3–0.4 or less) means tighter hips and lower risk.
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A higher DI (>0.5) suggests looser hips and increased risk, even if the dog hasn’t yet developed dysplasia.
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Look for consistency across generations here, too.
Final Tips for Breeding Soundness
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Don’t be fooled by a single score. Look at the pattern of health across 2–3 generations.
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Breeders aiming to improve the breed prioritize lines with:
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Low, consistent DI scores
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Multiple generations of Excellent or Good hips
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Normal elbows, patellas, and skeletal health
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Always combine orthopedic data with overall conformation, temperament, and breed-specific health testing.